CNBC's Jim Cramer said Monday that a new type of investor is behaving differently during the stock market's pandemic-era rally than what he has traditionally observed over his decades-long career on Wall Street and in financial media.

"There's a new young crop of buyers who do not sell on the news," Cramer said on "Squawk Box." "They're very differently from the older buyers. They don't seem to want to sell. They see good news and then they buy, and then no one comes forward to sell. It's rather remarkable. We haven't seen this pattern ever."

Cramer's comments before Monday's opening bell followed the announcement from American biotech company Moderna that its coronavirus vaccine was more than 94% effective. The positive development sent Moderna soaring in the premarket, while also pushing U.S. stock futures higher. The Dow Jones Industrial Average later was up more than 400 points during morning trading. Moderna, whose shares were up nearly 400% in 2020 was higher by over 7%.

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