Figuring out how to turn your latest business idea into the next big thing doesn't happen overnight, even if you’re a genius in your industry. Mark Zuckerberg is a great example. The Ivy League programming prodigy started off by overwhelming one of Harvard’s network switches with a site that let users choose the most attractive person from a group of photos.

Although FaceMash was quickly shut down by the university, it sparked an idea in Zuckerberg (or the Winklevoss twins, depending on who you ask), and he began writing code for “Thefacebook” the following semester. The little social site that would eventually grow into the Facebook we know today — and it’s currently worth an estimated $45 billion.

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