Familial hypercholesterolemia (FH) is a common but underdiagnosed and undertreated genetic disorder that affects individuals of all races and ethnicities. Several forms of FH have been identified. Heterozygous FH, the most common type, occurs when a mutation is inherited from one parent; conversely, homozygous FH occurs when the same mutation is inherited from both parents.

Estimates suggest that heterozygous FH affects 1 in 200-250 individuals worldwide. Without effective treatment, both heterozygous and homozygous FH lead to premature morbidity and mortality as a result of atherosclerotic cardiovascular disease. Despite a global call to action from the World Health Organization, it is believed that only 10% of individuals with FH are diagnosed and adequately treated.

How much do you know about heterozygous FH? Test yourself with this quick quiz.

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