Good morning.

Last week, in the midst of a worsening pandemic came a rare bright spot: Pfizer and Moderna announced that their vaccines were 90 percent effective or better against Covid-19. The news came as cases in California soared and 28 counties were moved back to the most restrictive tier.

The two drug companies said they would apply to the Food and Drug Administration for emergency authorization within weeks. And this morning, a third drugmaker announced promising results: AstraZeneca said early data showed its coronavirus vaccine was potentially up to 90 percent effective.

We know that once a vaccine is approved, there are many questions about how it will be rolled out to the public. Last month, Gov. Gavin Newsom created an 11-member Scientific Safety Review Workgroup, made up of esteemed scientists from around the state, tasked with independently reviewing vaccines for safety. Officials are also working with the Centers for Disease Control and Prevention to begin planning vaccine distribution in advance, working out the logistics of how they will supply vaccines to some 40 million residents.

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